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PUMA-mediated copanlisib-induced apoptosis. A WT and PUMA-KO HCT116... |  Download Scientific Diagram
PUMA-mediated copanlisib-induced apoptosis. A WT and PUMA-KO HCT116... | Download Scientific Diagram

Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* -  Journal of Biological Chemistry
Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry

PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53
PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53

FLIP(L) determines p53 induced life or death | bioRxiv
FLIP(L) determines p53 induced life or death | bioRxiv

FLIP(L) determines p53 induced life or death | bioRxiv
FLIP(L) determines p53 induced life or death | bioRxiv

Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells
Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells

A p53/lnc‐Ip53 Negative Feedback Loop Regulates Tumor Growth and  Chemoresistance - Zhang - 2020 - Advanced Science - Wiley Online Library
A p53/lnc‐Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance - Zhang - 2020 - Advanced Science - Wiley Online Library

HCT116 p53+/+ and its isogenic knockout (p53−/−, PUMA−/−, Bax−/−,... |  Download Scientific Diagram
HCT116 p53+/+ and its isogenic knockout (p53−/−, PUMA−/−, Bax−/−,... | Download Scientific Diagram

Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and  NF-κB to suppress tumor cell growth | Oncogene
Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth | Oncogene

The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced  by DNA Damage
The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced by DNA Damage

The Multi-Targeted Kinase Inhibitor Sunitinib Induces Apoptosis in Colon  Cancer Cells via PUMA | PLOS ONE
The Multi-Targeted Kinase Inhibitor Sunitinib Induces Apoptosis in Colon Cancer Cells via PUMA | PLOS ONE

Figures and data in Prosurvival long noncoding RNA PINCR regulates a subset  of p53 targets in human colorectal cancer cells by binding to Matrin 3 |  eLife
Figures and data in Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 | eLife

A, p53-KO HCT116 cells were incubated with aciculatin (5–10 µM) for 48... |  Download Scientific Diagram
A, p53-KO HCT116 cells were incubated with aciculatin (5–10 µM) for 48... | Download Scientific Diagram

Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and  NF-κB to suppress tumor cell growth | Oncogene
Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth | Oncogene

The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced  by DNA Damage
The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced by DNA Damage

p53-dependent p21 induction suppresses 17-AAGinduced apoptotic. A,... |  Download Scientific Diagram
p53-dependent p21 induction suppresses 17-AAGinduced apoptotic. A,... | Download Scientific Diagram

Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER  stress-induced p53-independent PUMA expression
Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression

PKR, a p53 target gene, plays a crucial role in the tumor-suppressor  function of p53 | PNAS
PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53 | PNAS

Puma is an essential mediator of p53-dependent and -independent apoptotic  pathways - ScienceDirect
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways - ScienceDirect

Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent  Suppression of Oxidative Phosphorylation - ScienceDirect
Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation - ScienceDirect

Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* -  Journal of Biological Chemistry
Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry

The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis -  ScienceDirect
The Mitochondrial Protein MAVS Stabilizes p53 to Suppress Tumorigenesis - ScienceDirect

Enhanced p53 activity synergizes with 17-AAG to induce PUMA and... |  Download Scientific Diagram
Enhanced p53 activity synergizes with 17-AAG to induce PUMA and... | Download Scientific Diagram

The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced  by DNA Damage
The Nuclear Function of p53 Is Required for PUMA-Mediated Apoptosis Induced by DNA Damage

Cancers | Free Full-Text | p53-Mediated Tumor Suppression: DNA-Damage  Response and Alternative Mechanisms | HTML
Cancers | Free Full-Text | p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms | HTML

PUMA is directly activated by NF-κB and contributes to TNF-α-induced  apoptosis | Cell Death & Differentiation
PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis | Cell Death & Differentiation

p300 regulates p53-dependent apoptosis after DNA damage in colorectal  cancer cells by modulation of PUMA/p21 levels | PNAS
p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels | PNAS

Sp1 and p73 activate PUMA following serum starvation
Sp1 and p73 activate PUMA following serum starvation

BITC treatment causes G2/M phase cell cycle arrest in PUMA knockout HCT-116  cells.
BITC treatment causes G2/M phase cell cycle arrest in PUMA knockout HCT-116 cells.

PUMA is directly activated by NF-κB and contributes to TNF-α-induced  apoptosis | Cell Death & Differentiation
PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis | Cell Death & Differentiation